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North American Pharmacist Licensure Examination

Last Update 12 hours ago Total Questions : 154

The North American Pharmacist Licensure Examination content is now fully updated, with all current exam questions added 12 hours ago. Deciding to include NAPLEX practice exam questions in your study plan goes far beyond basic test preparation.

You'll find that our NAPLEX exam questions frequently feature detailed scenarios and practical problem-solving exercises that directly mirror industry challenges. Engaging with these NAPLEX sample sets allows you to effectively manage your time and pace yourself, giving you the ability to finish any North American Pharmacist Licensure Examination practice test comfortably within the allotted time.

Question # 4

Which of the following statements is true regarding Drug-receptor bonds?

A.

Covalent bonds of drugs with receptors are strong and mostly reversible

B.

Covalent bonding is much more common than electrostatic bonding in drug-receptor interactions

C.

Electrostatic bonds are stronger than covalent bonds

D.

Hydrophobic bonds are weak bonds and they are important in the interactions of highly water soluble drugs with the lipids of cell membranes

E.

Bond formation of between the acetyl group of aspirin and cyclo-oxygenase enzyme is a covalent bond

Question # 5

In a study where Rivaroxaban was compared to enoxaparin to find total VTE following HIP replacement surgery, there were 17 total VTE out of 1513 patients in the Rivaraoaban group and 57 total VTE out of 1473 patient in the enoxaparin group. What is the relative risk reduction of using Rivaroxaban over Enoxaparin?

A.

39%

B.

71%

C.

29%

D.

14%

E.

42%

Question # 6

If you mix 30 gm 5% lidocaine cream and 90gm of 0.5% hydrocortisone cream, what percent of lidocaine and hydrocortisone do you have as the end product?

A.

Lidocaine/Hydrocortisone 2%/1.25%

B.

Lidocaine/Hydrocortisone 0.375%/0.15%

C.

Lidocaine/Hydrocortisone 1.25 %/ 0.15%

D.

Lidocaine/Hydrocortisone 2% /0.25%

E.

Lidocaine/Hydrocortisone 1.25% /0.375%

Question # 7

A physician needs your help to calculate the protamine dose on a patient who started hemorrhaging while on heparin. Patient has been receiving heparin at a dose of 13mls/hr for 2 hrs when the physician decides to use protamine to reverse the heparin. Heparin bag says concentration of 50 units/ml. The half-life of heparin is 60 minutes. 1 mg of protamine reverses 100 units of heparin.

How much protamine should be given to this patient?

A.

5mg

B.

10mg

C.

7mg

D.

13mg

E.

9.7mg

Question # 8

Which of the following is considered first-line therapy for reducing the risk of atherosclerotic cardiovascular disease (ASCVD)?

A.

HMG Co-A reductase inhibitors

B.

Bile acid resins

C.

Nicotinic Acid

D.

Fibrates

E.

Fish oil

Question # 9

A physician orders 300gms of albumin post paracentesis, how many milliliters of 25% albumin do you need to give 300gms?

A.

300ml

B.

25ml

C.

100ml

D.

1200ml

E.

1000ml

Question # 10

Alteplase is ordered for a 72 YOM who weighs 68kg for Ischemic stroke. The ER physician would like you to dose. As an ER pharmacist you know the dose is 0.9 mg/kg IV (not to exceed 90 mg); give 10% of the total dose as an IV bolus over 1 minute, then give the remaining 90% as an IV infusion over 60 minutes. After reconstitution, the concentration of Altaplace is 1mg/ml. How many ml is needed for the bolus and how many ml is needed for the infusion? Round to the nearest ml.

A.

6ml IV bolus, followed by 55mL IV over 60 minutes

B.

4ml IV bolus, followed by 57mL IV over 60 minutes

C.

3ml IV bolus, followed by 58mL IV over 60 minutes

D.

8ml IV bolus, followed by 52mL IV over 60 minutes

E.

9ml IV bolus, followed by 82mL IV over 60 minutes

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